Glucosamine is a sugar-and-amino acid compound naturally produced in the body and plays an important role in building cartilage, the firm, rubbery tissue that cushions our bones at the joints, and allows bones to move smoothly over one another. As we age, our body's capacity to produce glucosamine diminishes and the cartilage could break down and wear away. This could possibly result to joint pain and other diseases related with our joints such as osteoarthritis.
Tests have shown that a daily supplement of glucosamine helps prevent the advancement of cartilage deterioration, reduce joint pain and helps stimulate the production of new cartilage. In addition, an increasing number of evidence showed that it is effective in easing inflammation and pain of osteoarthritis. Studies reporting helpful effects have generally used glucosamine and chondroitin sulphate. The use of these joint supplements has few side effects and considered safe when taken in recommended doses. The usual recommended dose of Glucosamine sulfate is 1,500 milligrams and Chondroitin sulfate is 1,200; both in divided doses.
To obtain full benefits, more and more Orthopedists and other physicians advised patients to take both glucosamine and chondroitin sulphate. Studies were made to test the treatment effects of glucosamine and chondroitin and the progress experienced by the patients were the same as to those taking nonsteroidal anti-inflammatory drugs ("NSAIDs"). While there was an indication that NSAIDs may increase the development of arthritis, glucosamine and chondroitin may offer a more protective effect to the cartilage surface.
Glucosamine are from the exoskeleton of shellfish and those with allergies to shellfish should avoid taking the supplement. Studies showed conflicting effects on patients with diabetes, therefore it is recommended to seek medical advice before taking the supplements. Patients with heart disease, or any other illness, and are taking medications should also consult their physician. While there is not enough reliable scientific information available that indicates glucosamine sulfate is safe to take during pregnancy or while breastfeeding, it is best not to take the supplement while in this condition.